Oxidative Metabolism of Phenylacetic Acid by Penicillium Chrysogenum Q 176. (Addendum)
نویسندگان
چکیده
منابع مشابه
Oxidative Metabolism of Phenylacetic Acid by Penicillium chrysogenum Q-176. Part 6. The Production of Homogentisic Acid by a Mutant Strain Induced from Pen. chrysogenum
Penicillium chrysogenurn Q-176に よPhenylacetic Acidの 酸化的代謝 に關す る研 究(第6報) Pen. chyysognum Q-176 の1変 異 種 に よ るHomogentisic Acidの 生成 に つ い て (そ の2)Phenylacetic Acid代 謝 異 常 菌 株 の菌 学 的性 質 磯 野 正 雄(武田 薬品工業株式会社大阪工場) 昭 和28年10月24日 受 理 Oxidative Metabolism of Phenylacetic Acid by Penicillium chrysogenum Q-176. Part 6. The Production of Homogentisic Acid by a Mutant Strain Induced from Pen. chrysogenum Q-17...
متن کاملPenicillium chrysogenum Takes up the Penicillin G Precursor Phenylacetic Acid by Passive Diffusion.
Penicillium chrysogenum utilizes phenylacetic acid as a side chain precursor in penicillin G biosynthesis. During industrial production of penicillin G, phenylacetic acid is fed in small amounts to the medium to avoid toxic side effects. Phenylacetic acid is taken up from the medium and intracellularly coupled to 6-aminopenicillanic acid. To enter the fungal cell, phenylacetic acid has to pass ...
متن کاملOrganic acid metabolism of Penicillium chrysogenum. I. Lactate and acetate.
The media most useful for penicillin production contain corn-steep liquor (CSL), which has a high organic acid content. Such media usually contain about 5 mg./ml. lactic acid and rather less than 0-5 mg./ml. acetic acid. It has been found beneficial to include organic acids, especially the two mentioned, in synthetic media for penicillin production (Stone & Farrell, 1946; Jarvis & Johnson, 1947...
متن کاملThe oxidation of tricarboxylic acid cycle compounds by Penicillium chrysogenum.
The presence of a tricarboxylic acid cycle in Penicillium chry8ogenum, as yet, has not been demonstrated conclusively. Ajl (1951) stated that of the mechanisms proposed for oxidation of the 2 carbon fragment in mold metabolism, the evidence for a tricarboxylic acid cycle is the least convincing. This paper presents a study of some of the enzymes of the tricarboxylic acid cycle in cell-free prep...
متن کاملAcylation of 6-Aminopenicillanic Acid by Penicillium chrysogenum.
num deacylated phenoxymethylpenicillin about six times faster than benzylpenicillin to 6-aminopenicillanic acid (6-APA) (R. C. Erickson and R. E. Bennett, Bacteriol. Proc., p. 65, 1961; Erickson and Bennett, Appl. Microbiol. 13:738, 1965. This was observed with a penicillin-nonproducing strain, Wis 49408 (obtained from the University of Wisconsin), and with a penicillinproducing strain, P-5009 ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the agricultural chemical society of Japan
سال: 1958
ISSN: 0002-1407,1883-6844
DOI: 10.1271/nogeikagaku1924.32.12_937